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MIDAS Overview

Welcome to Methodological Innovation, Development, Adaptation & Support Theme (MIDAS)

MIDAS provides the methodological support that underpins all applied research in health, wellbeing and social care in ARC NWC. We achieve this through active engagement and collaboration with ARCNWC members and public/community advisers, developing and delivering research projects and providing training in different research approaches and methods.

Our work is underpinned by:

Health equity: we provide knowledge, tools and ideas on operationalising health equity in applied health research.

Capacity development: we offer guidance, training and support on using different methodologies. Link to training and education page

Public involvement: we involve the public in advising on, and co-producing our work. Link to public advisers’ page.

Contact for enquiries: ARCNWC-MIDAS@uclan.ac.uk

COVID 19 RESEARCH

MIDAS is undertaking exhaustive Covid-19 related systematic reviews:

1.) Hill et al., The prevalence and incidence of mental health conditions in healthcare workers during and after a pandemic. Ref: CRD42020181947. https://www.crd.york.ac.uk/PROSPERO

2.) Hill et al., The prevalence and incidence of mental health conditions in the general population during and after a pandemic. Reference: CRD42020182138. https://www.crd.york.ac.uk/PROSPERO

3.) Doherty, AJ., Benedetto, V., Harris, C., Hill, J., Boland P., Christian D., Bhutani G.E., Clegg, AJ. `The effectiveness of interventions for the psychological impacts on the general population and healthcare workers exposed to mass outbreaks: a systematic review.’ Reference: CRD42020182094. https://www.crd.york.ac.uk/PROSPERO

ARC NWC’s Coronavirus homepage can be found here.

Overarching aims:

•                    Building on existing CLAHRC NWC collaborations, further develop partnerships linking existing networks and groups to provide comprehensive, flexible, methodological infrastructure to support ARC- NWC.
•                    Provide integrated approaches to methodological support, linking Partners with experts through the Research and IMPACT Pipelines (diagrams 2&3), networking events and referral from a database of methodologists. Enable Partners to benefit from, and contribute to, on-going developments through innovation and adaptation to deliver applied research.
•                    Apply MIDAS’s knowledge and experience in: evidence synthesis, quantitative, qualitative, mixed- methods, behavioural science, realist approaches, health economics, embedding equity; to ensure partners submit competitive external grant applications and deliver robust research.
•                    Support Partners through the ‘Pipelines’: identifying Partners’ research needs, design and conduct of research, implementing and disseminating research findings in different settings. MIDAS will be central to process operationalisation, leading on methodological guidance and assessing evidence (see IMPACT section).
•                    Provide methodological training and capacity development to Partners and Public/Community Advisers.
•                    Ensure that all MIDAS activities are underpinned by co-production, integrating equity and capacity- building.

Objectives

Short-term (1-2 years)
•                    Co-develop with Themes, Partners and Public/Community Advisers operational and management structures and processes (Yr1).
•                    Establish methodological sub-groups (e.g. health economics, complex interventions, trials, health inequalities, evidence synthesis) developing networks integrating MIDAS to support research, provide education/training, build on methodological developments and foster innovation (Yr1). Led by senior academics, sub-groups will hold regular meetings/seminars, develop work programmes, and disseminate outputs (establish sub-groups/programmes Yr1; expand/promote Yr2).
•                    Promote MIDAS awareness at Theme Management Groups. Additionally, directors/leads for research/innovation/quality improvement, clinical specialisms (including NMAHPs), research groups and public events will be targeted (Yr1). Maintain regular contact through these links, via email, webpages and social media (Yr2-5).
•                    Identify cross-ARC methodological training requirements with Themes, Partners, Public/Community Advisers and postgraduate students; co-developing online resources/events (building on key handbooks and toolkits developed through CLAHRC NWC (Evaluation Workbook; HIAT; Implementation Summary Template) (Yr1). Ensure all core ARC NWC staff are trained in their use and promote awareness (Yr2). Evaluate and refine (Yr2).
•                    Contribute to educational events. Link with other Themes, Partners and external bodies (e.g. NW Evidence Synthesis Network) to collaborate/promote MIDAS’s and other seminars/training events (Yr2- 5:~6 seminars/year).
•                    Work with IMPACT to co-develop and operationalise ARC NWC Pipelines, establishing the infrastructure to support research and training delivery (Yr1). This includes identifying Partners’ research needs, methodological advice, co-producing applied research and supporting implementation/dissemination (Yr1-5).
•                    Co-produce evidence syntheses to establish the evidence base for interventions prior to progressing evaluations through the Pipelines (~2/year).
•                    Support publication of evidence syntheses/evaluations (Yr1-5).
•                    Collaborate with RDS and CTUs to explore requirements for establishing a framework for measuring cost-effectiveness where QALYs may not reflect outcomes, including innovative technologies (e.g. mHealth, End-of-Life) (yr2-4).
Medium-term (3-4 years)
•                    Co-develop a web-based resource, providing access to published evidence syntheses summaries to inform evaluations, prioritised and co-produced by Partners (Yr3-5:~8/year).
•                    Co-produce grant applications prioritised within ARC NWC (Yr3-5:~6/year). Undertake any funded.
•                    Increase co-produced evidence syntheses to reflect partner’s capacity development (Yr3-5:~3/year).
•                    Support the development and adaptation of research methods, promoting their use in evaluations produced by Partners through Pipelines (e.g. integration of network meta-analyses into economic evaluations; qualitative meta-synthesis, equity and realist approaches to inform guidelines and implementation).
•                    Build a new cross-ARC group led through health economics building expertise in discrete choice experiments (DCE). Partners and the public will be at core, building co-capacity and applying DCE, giving a new decision-making perspective on costs and benefits of providing interventions impacting health inequalities.
•                    Work with the CHI, IPH and EPHC Themes in assessing the cost-effectiveness of major public health programmes through natural experiments and collaborate on the analysis of longitudinal panel data from planned individual-household level data linkage. Support PCCC Theme in developing risk- prediction models e.g. for incident atrial fibrillation and pending crisis in epilepsy risk.
Long-term (5+ years)
•                    Deliver with ARC NWC Partners’ infrastructures to support ongoing development and maintenance of collaborative, sustainable, methodologist networks, building academic and Partner capacity, and attracting increasing external investment funding.

Proposed Outputs

•                    Online guidance and training resource on research methodology to support themes, Partners, Public/Community Advisers and postgraduate students, supplemented by courses/seminars (~24 seminars).
•                    Evidence syntheses (~13 syntheses) and summaries (~24 summaries), disseminated through the ARC- NWC website and public presentations, peer-reviewed and professional journals, and other media.
•                    Collaborative projects with other themes (e.g. economic evaluations/longitudinal analysis)
•                    Co-produced grant applications (~18 applications).
•                    A long-term development plan for sustaining methodology network in the NWC.

Research Strategy

MIDAS’ strategy will have three elements

Short-term (1-2 years)

•                    Co-develop with Themes, Partners and Public/Community Advisers operational and management structures and processes (Yr1).
•                    Establish methodological sub-groups (e.g. health economics, complex interventions, trials, health inequalities, evidence synthesis) developing networks integrating MIDAS to support research, provide education/training, build on methodological developments and foster innovation (Yr1). Led by senior academics, sub-groups will hold regular meetings/seminars, develop work programmes, and disseminate outputs (establish sub-groups/programmes Yr1; expand/promote Yr2).
•                    Promote MIDAS awareness at Theme Management Groups. Additionally, directors/leads for

1.       Early collaboration with themes ensuring it supports projects proposed by ARC NWC, both those already identified and emerging research;

2.       Work through the Pipelines to deliver applied research to evaluate interventions/services;

3.       Members will input expert methodological support tailored to needs and adapted as required, to deliver co-produced equity sensitive research and implementation across all ARC NWC themes and partnerships delivering expert methodological support and innovation.

Examples of impacts from theme team within CLAHRC NWC

1.        A CLAHRC NWC review of ‘The role of reading in adult and child mental health and wellbeing’ resulted in funding from Mersey Care NHS Trust (£170k) to assess the efficacy and impact of reading, through the READER’s Shared Reading model, with people who self-harm, in preparation for delivering this innovative intervention.
2.        CLAHRC NWC Partner Priority Programme evaluation of evidence on avoiding hospital admissions for type-three cancer patients, used by Clatterbridge Cancer Centre developing Clinical Nurse Specialists roles in targeted patient management thus improving quality of life, equity, and reduced unplanned care.
3.        Economic evaluations underpinning a range of CLAHRC NWC projects have influenced service development. These include: cost-effectiveness of improving access to support for those bereaved by suicide; renal function monitoring; harm minimisation; out of hospital treatment; public health systems resilience initiatives, and new diabetes care pathways

Key Contributing Researchers

    UCLan

Dr Louise Connell
Professor Soo Downe
Professor Lois Thomas
Professor Dame Caroline Watkins

    University of Lancaster

Professor Bruce Hollingsworth
Dr Siobhan Reilly

    University of Liverpool

Dr Angela Boland
Dr Rui Duarte
Professor Mark Gabbay
Dr Hendramoorthy Maheswaran
Professor Tony Marson
Professor Fiona Rowe
Professor Sally Sheard
Professor David Taylor-Robinson
Professor Nefyn Williams
Professor Paula Williamson
Professor Catrin Tudur Smith (Professor of Medical Statistics),
Professor Carrol Gamble (Professor of Medical Statistics)
Dr Girvan Burnside (Senior Lecturer in Biostatistics)
Professor Bridget Young

QUICK LINKS

Publications


CROSS CUTTING THEMES